解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Sungucine and isosungucine are two bisindole alkaloids isolated from the roots of the African plant Strychnos icaja Baillon. They both exhibit antiplasmodial activities but also show cytotoxic effects against human cancer cell lines. In order to elucidate their mechanism of action, we have investigated the interaction...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-32889
更新日期:2002-07-01 00:00:00
abstract::One new diterpene, 2 alpha-hydroxy-12beta-hydroxy-isopimara-8(14), 15-diene, and six known compounds as triterpenes, sterols and fatty acid, were isolated from the stem bark of Tanaecium jaroba (Bignoniaceae), a Bolivian plant used in traditional medicine. Their structures were established mainly by 1D and 2D NMR (COS...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32553
更新日期:2002-06-01 00:00:00
abstract::Calozeyloxanthone ( 1) was re-isolated from the root bark of Calophyllum moonii, an endemic species of Sri Lanka, and found to be active against vancomycin-resistant Enterococci (VRE) and vancomycin-sensitive Enterococci (VSE) with MIC values of 6.25 microg/ml and 12.5 microg/ml, respectively. Further, a marked synerg...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32558
更新日期:2002-06-01 00:00:00
abstract::We have examined the immunosuppressive effects of representative ginsenosides (Rb1, Rb2, Re and Rg1) from Panax ginseng C. A. Meyer on CD4+ and CD8+ lymphocyte proliferation. Ginsenosides differentially modulated lymphocyte proliferation induced by concanavalin A (Con A), lipopolysaccharide (LPS), phytohemaglutinin (P...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-32556
更新日期:2002-06-01 00:00:00
abstract::A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the ef...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32084
更新日期:2002-05-01 00:00:00
abstract::The ether fraction of the defatted ethanol extract of the aerial parts of Caralluma penicillata (defl) M. E. Br. (Asclepiadaceae) yielded four new oxypregnane glycosides, penicillosides D-G. The structures of the isolated compounds were established by different spectroscopic methods. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-32078
更新日期:2002-05-01 00:00:00
abstract::From the rhizome of Zingiber officinale L. (Zingiberaceae), four shogaols that protect IMR32 human neuroblastoma and normal human umbilical vein endothelial cells from beta-amyloid(25 - 35) insult at EC50 = 4.5 - 81 microM were isolated. The efficacy of cell protection from beta-amyloid(25 - 35) insult by these shogao...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-26757
更新日期:2002-04-01 00:00:00
abstract::(3R,6R)-4-methyl-6-(1-methylethyl)-3-phenylmethylperhydro-1,4-oxazine-2,5-dione (1) was isolated from the fruiting bodies of Isaria japonica as an apoptosis-inducing agent. The complete structural assignment of the compound was accomplished on the basis of spectroscopic methods and chemical transformations. Compound 1...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-26744
更新日期:2002-04-01 00:00:00
abstract::Protodioscin (NSC-698 796) is a furostanol saponin isolated from the rhizome of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for the treatment of cervical carcinoma, carcinoma of urinary bladder and renal tumor for centuries. To systematically evaluate its potential anticancer activity,...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-26743
更新日期:2002-04-01 00:00:00
abstract::A new furoclerodane, croblongifolin, together with one known clerodane, crovatin and one known labdane, nidorellol, were isolated from the stem bark of Croton oblongifolius. Structures were established based on spectroscopic and X-ray analysis. Croblongifolin showed a significant cytotoxicity against various human tum...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-23138
更新日期:2002-03-01 00:00:00
abstract::An arabinogalactan-protein (AGP) from suspension culture medium of Malva sylvestris was isolated by precipitation with beta-glucosyl Yariv reagent, followed by gel-permeation chromatography. It revealed characteristic features of AGPs: a high amount of polysaccharide with a ratio of galactose to arabinose of 1.9 : 1, ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-23127
更新日期:2002-03-01 00:00:00
abstract::Three new lycopodium alkaloids, 11alpha-hydroxyphlegmariurine B (2), 7alpha-hydroxyphlegmariurine B (3) and 7alpha,11alpha-dihydroxyphlegmariurine B (4) along with a known compound, phlegmariurine B (1), were isolated from the herb Huperzia serrata. The structures of the above compounds were elucidated based on spectr...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-20243
更新日期:2002-02-01 00:00:00
abstract::Volatile constituents of the essential oils from leaves and inflorescences of Solidago chilensis Meyen were analyzed by GC-FID, GC-MS and 13C-NMR and thirty-six different compounds were identified. Pumiloxide, an unusual labdane diterpene, was found to be one of the major components in both oils (15.3 % and 12.3 %, re...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-20253
更新日期:2002-02-01 00:00:00
abstract::Panaxytriol, a polyacetylenic compound, isolated from red ginseng (Panax ginseng C.A. Meyer), was studied to determine its effects on the growth and cell cycle of tumor cell lines. The compound showed both significant cytotoxicity and inhibition of DNA syntheses in various tumor cells tested. For P388D1, a mouse lymph...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-20240
更新日期:2002-02-01 00:00:00
abstract::As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded reverse transcriptase (RT). These compounds were found to be inactive in both the...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-20058
更新日期:2002-01-01 00:00:00
abstract::The culture medium of Beauveria amorpha Hohn. exhibited strong radical scavenging properties. Activity-directed fractionation assisted by a radical scavenging assay on TLC afforded two active compounds which were identified as 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-beta-D-glucopyranoside (1) and (-)-terredionol (2). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-19868
更新日期:2002-01-01 00:00:00
abstract::The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-20050
更新日期:2002-01-01 00:00:00
abstract::Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans agai...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-18838
更新日期:2001-12-01 00:00:00
abstract::Shoot-tips from several genotypes of the cardenolide-producing perennial shrub Digitalis obscura L. were successfully cryopreserved using the encapsulation-dehydration technique. Precultivation on MS medium containing 0.5 M sucrose, followed by 2.5 h dehydration (final weight 30 %) induced shoot regrowth in 42 % of cr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-18861
更新日期:2001-12-01 00:00:00
abstract::A new lignan glycoside, named eleutheroside E(2) (1), has been isolated from the roots of Eleutherococcus senticosus (known as "Siberian ginseng"), along with isomaltol 3-O-alpha-D-glucopyranoside (2), eleutherosides B, E and E(1), and thymidine. The structure of 1 was established by spectral interpretations as episyr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-18352
更新日期:2001-11-01 00:00:00
abstract::Bioassay-guided fractionation of the H(2)O extract of the seeds of Psoralea corylifolia furnished one hepatoprotective compound, bakuchiol (1), together with two moderately active compounds, bakuchicin (2) and psoralen (3), on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. The EC(50) values of compo...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-18347
更新日期:2001-11-01 00:00:00
abstract::We have previously reported that saiboku-to, an Oriental herbal remedy composed of a mixture of 10 different herbal extracts, possesses anti-histamine release effect on mast cells in rats. This effect may be due mainly to the extract of the bark of Magnolia obovata (M. obovata), a constituent herb of saiboku-to. In th...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-18354
更新日期:2001-11-01 00:00:00
abstract::Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-17365
更新日期:2001-10-01 00:00:00
abstract::Evodiamine, a major alkaloidal principle of Evodia fruits (Evodia rutaecarpa, Rutaceae), showed vanilloid receptor agonistic activities comparable to capsaicin. The Chinese literature refers to Evodia fruits as a "hot nature" herb. In spite of the similarities in the actions of evodiamine and capsaicin in vitro, evodi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-17353
更新日期:2001-10-01 00:00:00
abstract::The essential oil composition of three Zingiberaceae widely used as medicinal aromatic plants from S. Tomé and Príncipe: Aframomum danielli (Hook. f.) K. Schum., Curcuma longa L. and Zingiber officinale Rosc. was studied. Two samples of the essential oils from fruit of A. danielli and from rhizomes of the other two sp...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-16494
更新日期:2001-08-01 00:00:00
abstract::A new cytotoxic cyclopenta[b]benzofuran derivative, aglaiformosanin (1) and three known cyclopenta[b]benzofuran derivatives (2 - 4) were isolated from the stem bark of Aglaia formosana. Compounds 1 - 4 exhibited potent cytotoxicity against the P-388, KB, HT-29, HL-60, and A549 cell lines. The structure of compound 1 w...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-16471
更新日期:2001-08-01 00:00:00
abstract::Thirty-five flavonoids of seven different types, namely isoflavonoids, chalcones, dihydroflavonols, flavanols, flavanones, flavones, and flavonols were investigated for their ability to inhibit ascorbate-induced microsomal lipid peroxidation and their cytotoxicity. For each activity a structure-activity relationship w...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-16472
更新日期:2001-08-01 00:00:00
abstract::From Polygonum hydropiper L., a C13-norisoprenoid glucoside was isolated and its absolute configuration was established to be (6S,9S)-roseoside (1) by spectroscopic evidence and X-ray crystallographic analysis of its acetate derivative (2). In addition, the stereostructure of roseoside from Canthium subcordatum was re...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-15812
更新日期:2001-07-01 00:00:00
abstract::This Paper describes an improved HPLC method for the determination of pentacyclic oxindole alkaloids in Uncaria tomentosa (Cat's Claw). Six of the isomeric compounds could be baseline separated at room temperature within less than 30 min by using 3 microm C-18 column material and a mobile phase consisting of 10 mM pho...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-15824
更新日期:2001-07-01 00:00:00
abstract::The inhibition of aflatoxin B1 (AFB1) metabolism by a water extract of the root of Scutellaria baicalensis and its flavonoids was examined in liver microsomes. AFB1 is known to be metabolized to aflatoxin M1 (AFM1), aflatoxin Q1 (AFQ1), and AFB1-8,9-epoxide (AFBO). The water extract potently inhibited the production o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-15810
更新日期:2001-07-01 00:00:00
abstract::We previously reported the isolation of eleven new cardiac glycosides called cheiranthosides I-XI together with two known ones (olitoriside and erysimoside) from the seeds of Erysimum cheiranthoides L. The glycosides were evaluated for their inhibitory activity against Na+,K(+)-ATPase by comparing with typical cardiac...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-14309
更新日期:2001-06-01 00:00:00
abstract::Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3'-O-methyl-4'-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4-methylenedioxy-3'-O-methyl ellagic acid (3), 3,3'-di-O-methyl ellagic acid (4) and 3,3',4'-tr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-14306
更新日期:2001-06-01 00:00:00
abstract::We report a sensitive method for the estimation of quinine (Qn), cinchonine (Cn), and cinchonidine (Cnd) and a new method based on fluorescence enhancement and detection and quantification of quinidine (Qnd) from Cinchona stem bark and its formulations, using HPTLC. Standard solutions of Qn, Qnd, Cn, and Cnd were appl...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-11995
更新日期:2001-04-01 00:00:00
abstract::One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-12007
更新日期:2001-04-01 00:00:00
abstract::Ginsenosides are the major principles of Panax ginseng C. A. Meyer (Araliaceae) used as a mild oriental folk medicine. In this report, we have examined the inhibitory potency of protopanaxadiol ginsenosides (PPDGs) such as Rb1, Rb2 and Rc, and their co-treatment effect with known tumor necrosis factor (TNF)-alpha anta...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-12005
更新日期:2001-04-01 00:00:00
abstract::Three new steroidal saponins were isolated from the fruits of Tribulus terrestris, and their structures were elucidated as (25R,S)-5 alpha-spirostane-12-one-3 beta-ol-3-O-beta-xylopyranosyl(1-->2)- [beta-xylopyranosyl(1-->3)]-beta-glucopyranosyl(1-->4)-[alpha-rhamno- pyranosyl(1-->2)]-beta-galactopyranoside; 26-O-beta...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-11650
更新日期:2001-03-01 00:00:00
abstract::Cnidicin (1) and five related coumarins were isolated from the root extract of Angelica koreana (Umbelliferae) as active principles responsible for the inhibitory effect on the degranulation process of cultured mast cells. Cnidicin (1) demonstrated a significant inhibition upon the release of beta-hexosaminidase from ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-11509
更新日期:2001-03-01 00:00:00
abstract::The neuroprotective effects of spiramine T, an atisine-type diterpenoid alkaloid isolated from the Chinese herbal medicine Spiraea japonica var. acuta (Rosaceaee), on cerebral ischemia-reperfusion injury produced by 10-min bilateral occlusion of the common carotid arteries followed by 5-day reperfusion in gerbils were...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-11510
更新日期:2001-03-01 00:00:00
abstract::The essential oils of Salvia ringens (samples A and B), were analyzed by means of GC and GC/MS. From the seventy-five identified constituents representing 99.82 and 99.86% of the oils, 1,8-cineole and alpha-pinene were the major components. Furthermore, sample B exhibited a very interesting antimicrobial profile after...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-10627
更新日期:2001-02-01 00:00:00
abstract::The present study was designed to investigate the mechanism of action of n-butylidenephthalide on the deficits of inhibitory avoidance performance induced by drugs in rats with piracetam as a positive control. n-Butylidenephthalide attenuated the scopolamine-induced and mecamylamine-induced acquisition impairment, and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-10631
更新日期:2001-02-01 00:00:00